Understanding PANDAS with reseracher, Dr. Madeleine Cunningham


Champaign, Ill. (WCIA)

Heather Roberts, sits down virtually with Madeleine W Cunningham, PhD, to share information on PANDAS/PANS.

*Web Extra*

PANDAS is an acronym for Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infection. It is an autoimmune condition initially triggered by strep infections, which disrupts a child’s normal neurologic activity.

PANS is an acronym for Pediatric Acute-onset Neuropsychiatric Syndrome, which is associated with a variety of different infections, whereas PANDAS is a disorder associated with only streptococcal infections—specifically group A strep. Although the etiology for PANS is different from PANDAS the symptom presentation is nearly identical.

PANS and PANDAS are infection-induced autoimmune conditions that disrupt a patient’s normal neurologic functioning, resulting in a sudden onset of Obsessive Compulsive Disorder (OCD) and/or motor tics.

PANS and PANDAS can include a variety of other symptoms such as anorexia (food restrictions), anxiety, irritability, hyperactivity, sleep disturbances, mood swings and urinary problems.

Children with PANS and PANDAS are often misdiagnosed and obtaining a correct diagnosis can be challenging, because PANS and PANDAS symptoms can mimic other illnesses.

Studies have shown that when given appropriate anti-infective and/or immunological treatment, PANS and PANDAS patients experience symptom resolution, or their symptoms are dramatically reduced.

The similarities and differences between PANS and autism, if PANDAS is really autoimmune encephalitis, what it would take for the Cunningham Panel to gain widespread acceptance,

Cunningham Panel™ can aid in the diagnosis of PANS and PANDAS.

The Cunningham Panel™ of tests can assist you in diagnosing these treatable autoimmune neurologic disorders.

PANS and PANDAS are clinical diagnoses, therefore it is very important to have a physician who understands this condition.

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